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ETOFYLLINE CLOFIBRATE

Product Name
ETOFYLLINE CLOFIBRATE
CAS No.
54504-70-0
Chemical Name
ETOFYLLINE CLOFIBRATE
Synonyms
duolip;ml1024;Theofibrate;etofyllinclofibrat;etofyllinclofibrate;ETOFYLLINE CLOFIBRATE;Etofylline cIofibrate;ETOFYLLINE CLOFIBRATE USP/EP/BP;yl-2,6-dioxo-7h-purin-7-yl)ethylester;1-(7-theophyllinyl)-2-ethyl(2-(p-chlorophenoxy)isobutyrate)
CBNumber
CB1312915
Molecular Formula
C19H21ClN4O5
Formula Weight
420.85
MOL File
54504-70-0.mol
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ETOFYLLINE CLOFIBRATE Property

Melting point:
133-135°
Boiling point:
615.8±65.0 °C(Predicted)
Density 
1.3758 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
Store at -20°C
solubility 
DMSO: 52 mg/mL (123.56 mM)
solubility 
DMSO: 52 mg/mL (123.56 mM)
pka
0.17±0.70(Predicted)
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Safety

Toxicity
LD50 in mice, rats, dogs (g/kg): 11.7, 17.0, >10.0 orally (Metz et al.)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015827
Product name
ETOFYLLINE CLOFIBRATE
Purity
95.00%
Packaging
100MG
Price
$290.85
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015827
Product name
ETOFYLLINE CLOFIBRATE
Purity
95.00%
Packaging
1G
Price
$945.95
Updated
2021/12/16
Crysdot
Product number
CD11107001
Product name
Etofyllineclofibrate
Purity
95+%
Packaging
1g
Price
$987
Updated
2021/12/16
AHH
Product number
MT-51709
Product name
Etofyllineclofibrate
Purity
98%
Packaging
5g
Price
$910
Updated
2021/12/16
Chemenu
Product number
CM138513
Product name
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl2-(4-chlorophenoxy)-2-methylpropanoate
Purity
95%
Packaging
1g
Price
$931
Updated
2021/12/16
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ETOFYLLINE CLOFIBRATE Chemical Properties,Usage,Production

Originator

Duolip,Merckle,W. Germany,1981

Uses

Duolip (L. Merckle, Germany).

Definition

ChEBI: Etofylline clofibrate is an oxopurine.

Manufacturing Process

107.3 g (0.5 mol) 2-(p-chlorophenoxy)isobutyric acid and 56.0 g (0.25 mol) 7-hydroxyethyltheophylline were suspended together in 250 ml xylene. They were heated together for 15 hours in a water separator following the addition of 1.5 g p-toluenesulfonic acid. The solution was next agitated with dilute sodium bicarbonate solution (0.5 mol NaHCO3), water washed and evaporated in a rotary evaporator.
The residue was then crystallized from isopropanol, yielding 58.0 g (55% yield) of 1-(7-theophyllinyl)-2-ethyl[2-(p-chlorophenoxy)-isobutyrate] . The compound had a melting point of 131°C to 132°C.

Therapeutic Function

Antihyperlipidemic

ETOFYLLINE CLOFIBRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ETOFYLLINE CLOFIBRATE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Etofylline Clofibrate 54504-70-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-11
Career Henan Chemical Co
Product
ETOFYLLINE CLOFIBRATE 54504-70-0
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-20

54504-70-0, ETOFYLLINE CLOFIBRATERelated Search:


  • ETOFYLLINE CLOFIBRATE
  • 1-(7-theophyllinyl)-2-ethyl(2-(p-chlorophenoxy)isobutyrate)
  • 1-(theophyllin-7-yl)-aethyl-22-(p-chlorphenoxy)-2-methylpropionat
  • 1-(theophyllin-7-yl)-ethyl-22-(p-chlorophenoxy)-2-methylpropionate
  • duolip
  • etofyllinclofibrat
  • etofyllinclofibrate
  • ml1024
  • propionicacid,2-(4-chlorophenoxy)-2-methyl-,2-(1,2,3,6-tetrahydro-1,3-dimeth
  • yl-2,6-dioxo-7h-purin-7-yl)ethylester
  • Theofibrate
  • 2-(4-Chlorophenoxy)-2-methylpropionic acid [2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl] ester
  • 2-(4-Chlorophenoxy)-2-methylpropionic acid 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester
  • Etofylline cIofibrate
  • Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester
  • ETOFYLLINE CLOFIBRATE USP/EP/BP
  • 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
  • 54504-70-0
  • C19H21ClN4O5
  • API